Vastarel MR (35mg) 20 Tablets

Vastarel MR (35mg) 20 Tablets

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  • Manufacturer Servier Research and Pharmaceuticals [Pakistan] (Pvt.) Ltd.
  • Generic Name Trimetazidine Dihydrochloride
Rs. 265.33 Rs. 285.3
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Product Information

  • Description

    Trimetazidine dihydrochloride is a unique drug that operates as a metabolic modulator, specifically improving the uptake and utilization of glucose in insulin-sensitive tissues, most notably the myocardium. This drug works via enhancing the insulin-facilitated glucose transport pathway, which leads to increased efficiency of ATP production. Though it is not a substitute for ACE inhibitors or statins, it works by reducing the workload of the heart and relieving symptoms of angina by altering the way the heart muscle processes adenosine triphosphate (ATP, the universal energy currency of cells), thereby increasing the efficiency of ATP production. It is important to note that trimetazidine dihydrochloride does not address the underlying atherosclerotic process that causes most cases of angina and is not a substitute for immediate intervention when symptoms of angina occur. Furthermore, it is not intended to be a long-term drug, and patients will normally transition to alternative therapies after some time.

  • Ingredients

    Trimetazidine Dihydrochloride
  • Drug Class

    Pfox Inhibitors

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Management of stable angina pectoris.
    • Acute myocardial infarction.
    • Trimazidine Dihydrochloride Tablets are indicated for the prevention of anginal attacks in patients with chronic stable angina when the sublingual route is not feasible.
    • Trimazidine Dihydrochloride Tablets should be prescribed in the context of a supervised program that includes clinical evaluation and periodic measurements of exercise tolerance.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Trimetazidine is administered in the treatment of chronic stable angina, transient ischemic attacks, and cerebrovascular insufficiency.
    • For adults a starting dose of 50–100 mg two times a day, with or without food, should be taken. The dose can be increased up to a maximum of 400 mg daily in divided doses. Doses should be individualized according to the severity of the condition and response to therapy.
    • For elderly patients, the recommended starting dose is 50 mg two times a day. The dose may be increased if necessary and based on the patient's response to the therapy.
    • For children older than 15 years, a dose of 100–200 mg a day in divided doses is recommended and should be adjusted based on response and tolerability.
  • In case of Overdose

    If a patient has received an overdose of Trimazidine Dihydrochloride, it is crucial to seek medical attention immediately to ensure the best possible outcome for the patient. Some of the symptoms of overdose include:

  • Missed Dose

    It is crucial to adhere to the prescribed dosage of any medication, including Trimetazidine Dihydrochloride 35mg. If you happen to miss a dose, take it as soon as possible unless it is close to the time for your next scheduled dose. If so, it is advised to skip the missed dose and resume your regular dosage schedule. It is important to not double up or take extra doses to make up for the missed medication as this may lead to an overdose or adverse side effects. If you have any questions or concerns about missing a dose, it is always best to consult your doctor or pharmacist for guidance regarding your specific situation.

  • How To Use

    The medicine TRIMETAZIDINE DIHYDROCHLORIDE is a drug that aids in the reduction of chest pain incidents caused by heart disease, it however, is not a cure. The recommended dose for adults and children above 12 years is one tablet taken three times a day, swallowed whole with water during meal times. If you miss a dose, it is advisable to take it as soon as possible within 4 hours of the usual time you take it. But if you miss a dose by more than 4 hours, it is best to skip the missed dose entirely and take the next dose as usual. Overdosing on the drug should warrant a call to your doctor or nearest hospital for immediate advice. This drug may cause dizziness or light-headedness, so it is best to sit or lie down if you feel this way and seek medical advice if the feeling persists. Inform your doctor or pharmacist of your medical history comprising of heart, kidney, liver, and diabetes issues before taking TRIMETAZIDINE DIHYDROCHLORIDE. This medicine may also cause nausea or vomiting, so it is advisable to take it with food to minimize the incidence of feeling sick. If you experience sickness even with food, talk to your doctor or pharmacist for advice on how to cope with the side effect. It is important to note that you should not drive while taking this medicine.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Are allergic to Trimazidine Dihydrochloride or any of the other ingredients in the medication
    • Have asthma or other breathing problems
    • Are pregnant, planning to become pregnant, or breastfeeding
    • Have severe heartburn or indigestion
    • Have short breaths
    • Have experienced a heart attack or stroke within a recent time frame
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Dizziness
    • Headache
    • Weakness
    • Chest pain
    • Shortness of breath
    • Palpitations
    • Tremor
    • Agitation
    • Insomnia
    • Paranoia
    • Nausea
    • Vomiting
    • Diarrhea
    • Constipation
    • Loss of appetite
    • Weight loss
    • Ecstasy
    • Irritability
    • Paralytic constipation
    • A feeling of heaviness in the abdomen
    • Faecal incontinence
  • Storage/Disposal

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